Lung - Multiple Secondary Carcinoma Deposits - Erler Zimmer

Lung - Multiple Secondary Carcinoma Deposits in The Lung and Pleura - Erler Zimmer

Clinical History

This 47-year-old woman was admitted in the advanced stage of carcinomatosis. Upon examination, a firm liver and a mass on the right pelvic region were palpable. She had been experiencing constitutional symptoms for several months before seeking medical attention. Admission was for palliative care, and sadly, she passed away shortly thereafter.

Pathology

The left intact lung displays numerous pale tumor nodules of varying sizes scattered throughout its substance. Several nodules near the hilum are merged. Pale tumor tissue is present in the hilar lymph nodes. Small tumor nodules ranging from 2mm to 2cm can be observed beneath the thickened pleura on the costal, mediastinal, and diaphragmatic surfaces. Histologically, these were identified as metastatic deposits of adenocarcinoma. Post-mortem examination revealed an adenocarcinoma of the ovary with metastases in the lungs, heart, liver, and pericardium.

Further Information

Pulmonary metastases are more frequently encountered than primary lung cancer. Malignant diseases originating from any part of the body can spread to the lungs due to its rich blood supply and lymphatic drainage. Sarcomas typically metastasize through the bloodstream, while carcinomas spread via the bloodstream, the lymphatic system, or a combination of both.